Chemistry:6-Bromo-MDMA
From HandWiki
6-Bromo-MDMA, also known as 6-bromo-3,4-methylenedioxy-N-methylamphetamine or as 2-bromo-4,5-methylenedioxymethamphetamine (2-Br-4,5-MDMA), is a psychoactive drug of the phenethylamine, amphetamine, and MDxx families related to MDMA.[1][2][3] It does not appear to be a serotonin releasing agent like MDMA, but instead to be a serotonin reuptake inhibitor like citalopram, and with much greater serotonin transporter (SERT) affinity than MDMA.[1] Relatedly, 6-bromo-MDMA lacked key MDMA-like behavioral effects in rodents, including hyperlocomotion, enhanced active avoidance conditioning, and increased social interaction.[1] The drug was encountered as a novel designer drug in Europe in 2014.[2][3]
See also
- Substituted methylenedioxyphenethylamine
- 6-Bromo-MDA
- 6-Chloro-MDMA
- 6-Chloro-MDA
- DFMDA
References
- ↑ 1.0 1.1 1.2 "Aromatic Bromination Abolishes the Psychomotor Features and Pro-social Responses of MDMA ("Ecstasy") in Rats and Preserves Affinity for the Serotonin Transporter (SERT)". Frontiers in Pharmacology 10. 2019. doi:10.3389/fphar.2019.00157. PMID 30873030.
- ↑ 2.0 2.1 "EMCDDA-Europol 2014 Annual Report on the implementation of Council Decision 2005/387/JHA". 2 July 2024. https://www.euda.europa.eu/publications/implementation-reports/2014_en.
- ↑ 3.0 3.1 "Identification of five substituted phenethylamine derivatives 5-MAPDB, 5-AEDB, MDMA methylene homolog, 6-Br-MDMA, and 5-APB-NBOMe". Drug Testing and Analysis 9 (2): 199–207. February 2017. doi:10.1002/dta.1955. PMID 26856255.
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