Chemistry:Alphacetylmethadol

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Short description: Synthetic opioid analgesic drug
Not to be confused with acetylmethadol[1]
Alphacetylmethadol
Skeletal formulas of (R,R)-alphacetylmethadol (left), and (S,S)-alphacetylmethadol (right)
Ball-and-stick models of (R,R)-alphacetylmethadol (left), and (S,S)-alphacetylmethadol (right)
Clinical data
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC23H31NO2
Molar mass353.506 g·mol−1
3D model (JSmol)

Alphacetylmethadol (INN), or α-acetylmethadol (AAM), is a synthetic opioid analgesic.[2] Its levorotary enantiomer, levacetylmethadol, is an FDA-approved treatment for opioid addiction; however as of 2003 it is no longer used in the United States for this purpose.[2] Alphacetylmethadol is very similar in structure to methadone, a widely prescribed treatment for opioid addiction. In the United States , it is a Schedule I controlled substance under the Controlled Substances Act (presumably because it was never marketed in the US, as is the case with other common opiate/opioid medications such as heroin and prodine),[3] with an ACSCN of 9603 and a 2013 annual manufacturing quota of 2 grammes.[citation needed]

See also

References

  1. ↑ Richard Lawrence Miller (30 December 2002). The Encyclopedia of Addictive Drugs. Greenwood Publishing Group. p. 222. ISBN 978-0-313-31807-8. https://books.google.com/books?id=G7As-qawdzMC&pg=PA222. Retrieved 15 May 2012. 
  2. ↑ 2.0 2.1 "Heroin discriminative stimulus effects of methadone, LAAM and other isomers of acetylmethadol in rats". Psychopharmacology 164 (1): 108–14. October 2002. doi:10.1007/s00213-002-1198-8. PMID 12373424. 
  3. ↑ 21 U.S.C. § 812(b)(1)


fi:Metadoli#Johdannaiset



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