Chemistry:2,N,N-TMT

Short description: Chemical compound

2,N,N-TMT

Legal status
Legal status	DE: NpSG (Industrial and scientific use only) UK: Class A
Identifiers
IUPAC name (2-(2-methyl-1H-indol-3-yl)-1-methyl-ethyl)dimethylamine
CAS Number	1080-95-1 Y
PubChem CID	11820174
ChemSpider	9994827
UNII	P15UO6J3FK
ChEMBL	ChEMBL7580
Chemical and physical data
Formula	C13H18N2
Molar mass	202.301 g·mol−1
3D model (JSmol)	Interactive image
SMILES Cc1c(c2ccccc2[nH]1)CCN(C)C
InChI InChI=1S/C13H18N2/c1-10-11(8-9-15(2)3)12-6-4-5-7-13(12)14-10/h4-7,14H,8-9H2,1-3H3 Key:NDGCOWDSLVNLGE-UHFFFAOYSA-N
(verify)

2,N,N-trimethyltryptamine, 2,N,N-TMT, or 2-Me-DMT is a tryptamine derivative that is a psychedelic drug. It was invented by Alexander Shulgin and reported in his book TiHKAL (#34). It is claimed to show psychoactive effects at a dosage of 50–100 mg orally, but these are relatively mild compared to other similar drugs, suggesting that while the 2-methyl group has blocked the binding of metabolic enzymes, it is also interfering with binding to the 5HT_2A receptor target that mediates the hallucinogenic effects of these drugs.

Legal status

Sweden's public health agency suggested classifying 2-Me-DMT as a hazardous substance, on May 15, 2019.

See also

• 5,N,N-TMT
• 7,N,N-TMT

External links

• 2-Me-DMT entry in TiHKAL • info