Chemistry:4′-Fluorococaine
From HandWiki
Short description: Chemical compound
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| Formula | C17H20FNO4 |
| Molar mass | 321.348 g·mol−1 |
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4′-Fluorococaine is a tropane derivative drug which is a synthetic analogue of cocaine. Unlike related compounds such as the corresponding 4′-fluorophenyltropane derivative CFT and the 2′-hydroxy analogue salicylmethylecgonine, 4′-fluorococaine has only around the same potency as cocaine as an inhibitor of dopamine reuptake, but conversely it is a much stronger serotonin reuptake inhibitor than cocaine, resulting in a significantly altered pharmacological profile in animal studies.[1]
See also
References
- ↑ "Studies with differentially labeled [11C]cocaine, [11C]norcocaine, [11C]benzoylecgonine, and [11C]- and 4'-[18F]fluorococaine to probe the extent to which [11C]cocaine metabolites contribute to PET images of the baboon brain". Journal of Neurochemistry 62 (3): 1154–62. March 1994. doi:10.1046/j.1471-4159.1994.62031154.x. PMID 8113802.
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