Chemistry:5-TFMO-DMT
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Short description: Chemical compound
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| Other names | 5-OCF3-DMT |
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| Formula | C13H15F3N2O |
| Molar mass | 272.271 g·mol−1 |
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5-TFMO-DMT (5-(trifluoromethoxy)-DMT, 5-OCF3-DMT, 5-(trifluoromethoxy)-N,N-dimethyltryptamine) is a psychedelic tryptamine derivative related to drugs such as 5-MeO-DMT and DMT (DMT). It acts as an agonist at the 5-HT2A receptor with an EC50 of 127.2 nM.[1] It was shown to release serotonin (5-HT) from synaptosomal preparations, and to reduce immobility time in the forced-swim test in animal studies, suggesting that it might have antidepressant activity.[1]
See also
- 5-MeO-DMT
- 5-EtO-DMT
- 5-Fluoro-DMT
- 5-TFM-DMT
References
- ↑ 1.0 1.1 Kruegel AC, "NOVEL TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS.", WO patent 2022/235927, published 10 November 2022, assigned to Gilgamesh Pharmaceuticals, Inc..
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