Chemistry:O-2390

From HandWiki
Short description: Chemical compound
3,4-Dichloro-alpha-PVP
O-2390.svg
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC15H19Cl2NO
Molar mass300.22 g·mol−1
3D model (JSmol)

O-2390 (3,4-Dichloro-alpha-PVP, DCPVP) is a recreational designer drug from the substituted cathinone family, which acts as a potent inhibitor of dopamine and noradrenaline reuptake in vitro, with weaker but still significant inhibition of serotonin reuptake.[1][2][3][4]

See also

References

  1. "1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors". Journal of Medicinal Chemistry 49 (4): 1420–1432. February 2006. doi:10.1021/jm050797a. PMID 16480278. 
  2. "Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters". ACS Chemical Neuroscience 6 (10): 1726–1731. October 2015. doi:10.1021/acschemneuro.5b00160. PMID 26217965. 
  3. "Neurobiology of 3,4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP)". Brain Research Bulletin 126 (Pt 1): 111–126. September 2016. doi:10.1016/j.brainresbull.2016.04.011. PMID 27142261. 
  4. "Synthetic Cathinone Analogues Structurally Related to the Central Stimulant Methylphenidate as Dopamine Reuptake Inhibitors". ACS Chemical Neuroscience 10 (9): 4043–4050. September 2019. doi:10.1021/acschemneuro.9b00284. PMID 31369229.