Chemistry:List of naturally occurring phenethylamines

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Trichocereus macrogonus var. pachanoi, syn. Echinopsis pachanoi contain several phenethylamines.

Naturally occurring phenethylamines are organic compounds which may be thought of as being derived from phenethylamine itself that are found in living organisms.

Tyramine is a phenethylamine that occurs widely in plants[1] and animals, and is metabolized by various enzymes, including monoamine oxidases. Substituted phenethylamines like mescaline and lophophine are found in psychoactive cactus.

List of phenethylamines

Selected phenethylamines
Short Name Origin Rα R4 R5 RN1 RN2 Full Name
Phenethylamine Natural ? ? ? ? ? 2-phenylethan-1-amine
Hordenine Natural ? ? ? ? ? N,N-Dimethyltyramine
Lophophine Natural ? ? ? ? ? 3-methoxy-4,5-methylenedioxyphenethylamine
Mescaline Natural ? ? ? ? ? 3,4,5-trimethoxyphenethylamine
DMPEA Natural ? ? ? ? ? 3,4-dimethoxyphenethylamine
Tyramine Natural ? ? ? ? ?
Natural ? ? ? ? ? 3-hydroxy-4,5-dimethoxyphenethylamine
3-MT Natural ? ? ? ? ? 4-hydroxy-3-methoxyphenethylamine
Natural ? ? ? ? ? 4-hydroxy-3,5-dimethoxyphenethylamine

References

  1. T. A. Smith (1977) Phytochemistry 16 9-18.