Chemistry:2C-B-AN

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2C-B-AN, also known as 4-bromo-N-(α′-cyanobenzyl)-2,5-dimethoxyphenethylamine or as brolphetaminil, is a psychedelic drug of the phenethylamine, 2C, and N-benzylphenethylamine families related to 2C-B.[1][2][3] It is the derivative of 2C-B with a modified NBOMe-like N-(α′-cyanobenzyl) substitution.[1][2][3] The drug is chemically unstable and has been found to be a prodrug of 2C-B in vivo.[1][2][3] It is active at a dose of 50 mg orally and has a duration of 5 to 8 hours.[1][2][4] However, a wider dose range of 30 to 100 mg or more has also been reported.[4] 2C-B-AN has been described as producing stimulation and certain visual alterations.[1][4] It was described in the scientific literature by Daniel Trachsel in 2013, who cited personal communication with P. Rausch in 2009 as the source for the information.[1] 2C-B-AN was encountered as a novel designer drug in Europe by 2016.[2][4] It may be a controlled substance in Canada under phenethylamine blanket-ban language.[5] The drug is not an explicitly controlled substance in the United States.[6]

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 (in de) Phenethylamine: von der Struktur zur Funktion. Nachtschatten-Science (1 ed.). Solothurn: Nachtschatten-Verlag. 2013. pp. 843–843. ISBN 978-3-03788-700-4. OCLC 858805226. https://books.google.com/books?id=-Us1kgEACAAJ. 
  2. ↑ 2.0 2.1 2.2 2.3 2.4 "Prodrugs of New Psychoactive Substances (NPS): A New Challenge". Journal of Forensic Sciences 65 (3): 913–920. May 2020. doi:10.1111/1556-4029.14268. PMID 31943218. 
  3. ↑ 3.0 3.1 3.2 "The use of prodrugs as drugs of abuse". WIREs Forensic Science 6 (3). 2024. doi:10.1002/wfs2.1514. ISSN 2573-9468. https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/wfs2.1514. Retrieved 27 October 2025. 
  4. ↑ 4.0 4.1 4.2 4.3 Trott, Dominic Milton (12 September 2022). "2C-B-AN". The Drug Users Bible [Extended Edition]. MxZero Publishing. ISBN 978-0-9955936-9-5. https://drugusersbible.org/content/chemscape/psychedelics/2c-b-an/index.html. Retrieved 10 January 2026. 
  5. ↑ "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html. 
  6. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026, https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf 



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