Chemistry:3-(p-Fluorobenzoyloxy)tropane

Short description: Chemical compound

3-(p-Fluorobenzoyloxy)tropane

Clinical data
Routes of administration	insufflated
Legal status
Legal status	DE: Anlage II (Authorized trade only, not prescriptible)
Identifiers
IUPAC name (1R,5S)-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 4-fluorobenzoate
CAS Number	172883-97-5 Y
PubChem CID	5147770
ChemSpider	4321292 Y
UNII	MQP3G94388
Chemical and physical data
Formula	C15H18FNO2
Molar mass	263.312 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1C2CC(OC(C3=CC=C(F)C=C3)=O)CC1CC2
InChI InChI=1S/C15H18FNO2/c1-17-12-6-7-13(17)9-14(8-12)19-15(18)10-2-4-11(16)5-3-10/h2-5,12-14H,6-9H2,1H3 Y Key:YXDFSLSXLYAAPF-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

3β-(p-Fluorobenzoyloxy)tropane, (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 4-fluorobenzoic acid ester, 4-fluorotropacocaine, 3-Pseudotropyl-4-fluorobenzoate, 3-pseudotropyl-4-fluorobenzoate, pFBT) is a tropane derivative drug which acts as a local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic. It has been investigated as a potential radiolabelled agent for studying receptor binding, but was not adopted for this application. The main application for fluorotropacocaine, however, has been as a designer drug analogue of cocaine, first detected by the EMCDDA in 2008, and subsequently sold as an ingredient of various "bath salt" powder products, usually mixed in combination with other stimulant drugs such as caffeine, dimethocaine, desoxypipradrol or substituted cathinone derivatives.

See also

• Hygrine
• 4′-Fluorococaine
• Tropacocaine
• List of cocaine analogues