Chemistry:3C-BOH

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3C-BOH, also known as β-methoxy-3,4-methylenedioxyamphetamine (β-methoxy-MDA) or as BOMDA, is a psychoactive drug of the phenethylamine, amphetamine, MDxx, and BOx families related to 3,4-methylenedioxyamphetamine (MDA).[1][2] It is the β-methoxy derivative of MDA and the amphetamine (α-methyl) analogue of BOH (β-methoxy-MDPEA).[1][2] The drug is active at a dose of 40 to 70 mg orally with a duration of 3 to 6 hours.[1][2] It is said to produce "amphetamine-like effects", as well as physical side effects and temporary body stiffness.[1][2] 3C-BOH acts as a monoamine releasing agent and reuptake inhibitor, including of serotonin and norepinephrine, and additionally acts as an agonist of the serotonin 5-HT2 receptors, among other actions.[2] The compound can exist as four stereoisomers, with individual assessment of each individual isomer still needed.[1][2] 3C-BOH was first described in the scientific literature by Daniel Trachsel and colleagues in 2013 via personal communication with another person.[1][2]

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 (in de) Phenethylamine: von der Struktur zur Funktion. Nachtschatten-Science (1 ed.). Solothurn: Nachtschatten-Verlag. 2013. pp. 583. ISBN 978-3-03788-700-4. OCLC 858805226. https://books.google.com/books?id=-Us1kgEACAAJ. 
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 "Pharmacological characterization of 3,4-methylenedioxyamphetamine (MDA) analogs and two amphetamine-based compounds: N,α-DEPEA and DPIA". European Neuropsychopharmacology 59: 9–22. June 2022. doi:10.1016/j.euroneuro.2022.03.006. PMID 35378384. "3C-BOH has been described to have amphetamine-like effects in humans at doses of 40–70 mg, with a duration of 3–6 h (Trachsel et al., 2013). 3C-BOH can exist as four stereoisomers; the pharmacological assessment of each individual isomer is therefore necessary to gain insight into their effects.". 

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