Chemistry:4-Chloromethcathinone
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| Formula | C10H12ClNO |
| Molar mass | 197.66 g·mol−1 |
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| Melting point | 198 °C (388 °F) |
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4-Chloromethcathinone (also known as 4-CMC and Clephedrone) is a stimulant drug of the cathinone class that has been sold online as a designer drug.[1][2][3]
The exact pharmacology of 4-CMC is unknown, though it is probably a dopamine and serotonin releasing agent. Its chemical structure closely resembles para-Chloromethamphetamine and studies involving mice indicate that it is neurotoxic.[4]
Legality
Clephedrone is an Anlage I controlled drug in Germany.
Sweden's public health agency suggested classifying 4-Chloromethcathinone (klefedron) as illegal narcotic on June 1, 2015.[5]
As of October 2015 4-CMC is a controlled substance in China.[6]
4-CMC is considered a Schedule 1 substance in Virginia.[7]
In December 2019, the UNODC announced scheduling recommendations placing 4-CMC into Schedule II.[8]
See also
- 3-Chloromethcathinone
- 3-Methylmethcathinone
- 4-Bromomethcathinone
- 4-Chloroamphetamine
- 4-Cl-3-MMC
- 4Cl-PVP
- 4-Ethylmethcathinone
- 4-Methylmethcathinone
- Substituted cathinone
References
- ↑ "4-Chloromethcathinone". Cayman Chemical. https://www.caymanchem.com/app/template/Product.vm/catalog/16436.
- ↑ "Analysis and characterization of the novel psychoactive drug 4-chloromethcathinone (clephedrone)". Forensic Science International 244: e56–e59. November 2014. doi:10.1016/j.forsciint.2014.09.007. PMID 25280452.
- ↑ "Suicide attempt with a mix of synthetic cannabinoids and synthetic cathinones: Case report of non-fatal intoxication with AB-CHMINACA, AB-FUBINACA, alpha-PHP, alpha-PVP and 4-CMC". Forensic Science International 265: 121–124. August 2016. doi:10.1016/j.forsciint.2016.01.018. PMID 26890319.
- ↑ "Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles". Neurotoxicity Research 38 (2): 536–551. August 2020. doi:10.1007/s12640-020-00227-8. PMID 32506339.
- ↑ "23 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 1 June 2015. http://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2015/juni/23-nya-amnen-kan-klassas-som-narkotika-eller-halsofarlig-vara.
- ↑ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. http://www.sfda.gov.cn/WS01/CL0056/130753.html.
- ↑ "18VAC110-20-322. Placement of Chemicals in Schedule I." (in English). Commonwealth of Virginia. 2 December 2015. http://law.lis.virginia.gov/admincode/title18/agency110/chapter20/section322/.
- ↑ "World Health Organization recommends 12 NPS for scheduling". WHO. December 2019. https://www.unodc.org/LSS/Announcement/Details/021820a0-8746-42a4-9ee3-47ce50b30ca3.
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