Chemistry:Testosterone undecylenate
From HandWiki
Short description: Chemical compound
![]() | |
Clinical data | |
---|---|
Trade names | Durasteron, Triolandren (mixtures) |
Other names | TUe; Testosterone undecenoate; 17β-Hydroxyandrost-4-en-3-one 17β-(undec-10-enoate) |
Routes of administration | Intramuscular injection |
Drug class | Androgen; Anabolic steroid; Androgen ester |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
Chemical and physical data | |
Formula | C30H46O3 |
Molar mass | 454.695 g·mol−1 |
3D model (JSmol) | |
| |
|
Testosterone undecylenate (TUe) is an androgen/anabolic steroid medication and androgen ester which is no longer marketed.[1][2][3] It was a component of Durasteron and Triolandren, long-acting mixtures of testosterone esters in oil solution that were administered by intramuscular injection.[4][5][6][7]
See also
- Boldenone undecylenate
- Testosterone propionate/testosterone enanthate/testosterone undecylenate
- Testosterone propionate/testosterone valerate/testosterone undecylenate
- List of androgen esters § Testosterone esters
References
- ↑ "Notes - Long-Acting Androgens". The Journal of Organic Chemistry 21 (11): 1300–1302. 1956. doi:10.1021/jo01117a602. ISSN 0022-3263.
- ↑ "Long-acting Testosterone Esters. Some Considerations on their Biological Utilization1". Journal of the American Chemical Society 79 (16): 4472–4475. 1957. doi:10.1021/ja01573a061. ISSN 0002-7863.
- ↑ Meier, R; A Wettstein & E Lang, "Testosterone compositions", US patent 2855341, published 1958-10-07, assigned to Ciba pharmaceutical Products, Inc.
- ↑ Fertilitätsstörungen beim Manne. Springer-Verlag. 1960. pp. 260–. ISBN 978-3-642-94784-1. https://books.google.com/books?id=m1iqBgAAQBAJ&pg=PA260.
- ↑ Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. Gruyter. 1960. p. 153. ISBN 9783111138770. https://books.google.com/books?id=wcRsAAAAMAAJ.
- ↑ "Plasma testosterone values in different forms of testosterone treatment". Acta Endocrinologica 60 (3): 537–542. March 1969. doi:10.1530/acta.0.0600537. PMID 5395873. "Triolandren®, for intramuscular use, kindly supplied by Ciba, Basel, through Kobro 8c Co., Oslo, containing three different testosterone esters, in the following amounts of testosterone equivalents per ml oil: propionate 20 mg; valerate 80 mg; undecylenate 150 mg.".
- ↑ "Anabolic and androgenic effect of testosterone in sexually immature boys and its dependency on growth hormone". The Journal of Clinical Endocrinology and Metabolism 30 (1): 85–95. January 1970. doi:10.1210/jcem-30-1-85. PMID 4311616. "Triolandren, CIBA; 250 mg of this preparation contains 20 mg of testosterone propionate, 80 mg of testosterone-n-valerianate, and 150 mg of testosterone undecylenate—250 mg thus contains 173.8 mg of testosterone; the remaining 76.2 mg consists of the ester components [...]".
{{Navbox
| name = Androgens and antiandrogens | title = Androgens and antiandrogens | state = collapsed | listclass = hlist | groupstyle = text-align:center;
| group1 = Androgens
(incl. AAS)
| list1 =
| group2 = Antiandrogens | list2 = {{Navbox|child | groupstyle = text-align:center; | groupwidth = 9em;
| group1 = AR antagonists | list1 =
- Steroidal: Abiraterone acetate
- Canrenone
- Chlormadinone acetate
- Cyproterone acetate
- Delmadinone acetate
- Dienogest
- Drospirenone
- Medrogestone
- Megestrol acetate
- Nomegestrol acetate
- Osaterone acetate
- Oxendolone
- Potassium canrenoate
- Spironolactone
- Nonsteroidal: Apalutamide
- Bicalutamide
- Cimetidine
- Darolutamide
- Enzalutamide
- Flutamide
- Ketoconazole
- Nilutamide
- Seviteronel†
- Topilutamide (fluridil)
| group2 = Steroidogenesis| list2 =
inhibitors
| group3 = Antigonadotropins | list3 =
- D2 receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- Estrogens (e.g., bifluranol, [[diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
- GnRH agonists (e.g., leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Progestogens (incl., chlormadinone acetate, [[cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, [[Chemistry:Medroxyprogesterone medroxyprogesterone acetate, Chemistry:Megestrol acetate|megestrol acetate]])
| group4 = Others | list4 =
- Androstenedione immunogens: Androvax (androstenedione albumin)
- Ovandrotone albumin (Fecundin)
}}
| liststyle = background:#DDDDFF;| list3 =
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Androgen receptor modulators
- Estrogens and antiestrogens
- Progestogens and antiprogestogens
- List of androgens/anabolic steroids
}}
![]() | Original source: https://en.wikipedia.org/wiki/Testosterone undecylenate.
Read more |