Chemistry:Eutylone

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Short description: Designer drug of the cathinone class
Eutylone
Eutylone.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC13H17NO3
Molar mass235.283 g·mol−1
3D model (JSmol)
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Eutylone (also known as β-keto-1,3-benzodioxolyl-N-ethylbutanamine, bk-EBDB, and N-ethylbutylone) is a stimulant and empathogenic compound developed in the 1960s,[2][3] which is classified as a designer drug.[4] It was first reported to the EMCDDA in 2014 and became widespread internationally in 2019-2020 following bans on the related compound ephylone.[5][6][7][8] It is not a natural, but a synthetic cathinone.[8] In 2021, eutylone was the most common cathinone identified by the Drug Enforcement Administration in the United States.[9]

Legal status

Sweden's public health agency suggested classifying eutylone as a hazardous substance, on September 25, 2019.[10]

In the United States Eutylone is considered a schedule 1 controlled substance as a positional isomer of Pentylone.[11][12]

See also

References

  1. "Substance Details Eutylone". https://www.unodc.org/LSS/Substance/Details/29eff971-208a-4a67-98d6-71f53923862e. 
  2. "Aryl-α-aminoketone derivatives" GB patent 108513, published 1967-09-27, assigned to Boehringer Ingelheim
  3. "Eutylone and Its Structural Isomers Interact with Monoamine Transporters and Induce Locomotor Stimulation". ACS Chemical Neuroscience 12 (7): 1170–1177. April 2021. doi:10.1021/acschemneuro.0c00797. PMID 33689284. 
  4. "Eutylone". New Synthetic Drugs Database. 12 November 2023. http://nsddb.eu/substance/413/. 
  5. "Determining changes in new psychoactive substance use in Australia by wastewater analysis". The Science of the Total Environment 731: 139209. August 2020. doi:10.1016/j.scitotenv.2020.139209. PMID 32417485. Bibcode2020ScTEn.731m9209B. https://unisa.alma.exlibrisgroup.com/view/delivery/61USOUTHAUS_INST/12200648250001831. 
  6. "Eutylone Intoxications-An Emerging Synthetic Stimulant in Forensic Investigations". Journal of Analytical Toxicology 45 (1): 8–20. August 2020. doi:10.1093/jat/bkaa113. PMID 33325503. 
  7. "Analytically confirmed eutylone (bk-EBDB) exposure in emergency department patients". Clinical Toxicology 59 (9): 846–848. January 2021. doi:10.1080/15563650.2020.1868491. PMID 33448882. 
  8. 8.0 8.1 "A fatal case of intoxication from a single use of eutylone: Clinical symptoms and quantitative analysis results". Leg Med (Tokyo) 58: 102085. September 2022. doi:10.1016/j.legalmed.2022.102085. PMID 35537301. 
  9. "Emerging Threat Report". 2021. https://cesar.umd.edu/sites/cesar.umd.edu/files/pubs/DEA-Emerging-Threat-Report-2021-Mid-Year.pdf. 
  10. "Tretton ämnen föreslås klassas som narkotika eller hälsofarlig vara" (in sv). Folkhälsomyndigheten. 25 September 2019. https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2019/september/tretton-amnen-foreslas-klassas-som-narkotika-eller-halsofarlig-vara/. 
  11. Lists of: Scheduling Actions. Controlled Substances. Regulated Chemicals
  12. "Federal Register :: Request Access". https://www.federalregister.gov/documents/2023/04/10/2023-07335/specific-listing-for-eutylone-a-currently-controlled-schedule-i-substance.