Chemistry:Deschloroketamine
From HandWiki
Short description: Chemical compound
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| Formula | C13H17NO |
| Molar mass | 203.285 g·mol−1 |
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Deschloroketamine (DXE, DCK, 2'-Oxo-PCM) is a dissociative anesthetic[1][2] that has been sold online as a designer drug.[3][4][5][6][7] It has also been proposed for the treatment of bacterial, fungal, viral or protozoal infections and for immunomodulation at doses of 2 mg per day.[8]
History
In 2019, it became part of a group of molecules studied by the French laboratory Caulredaitens.[citation needed]
Legal status
Deschloroketamine is illegal in Latvia,[9] and is covered by blanket bans in Canada and the UK.[citation needed]
See also
- Ketamine
- 2-Fluorodeschloroketamine
- 3-Fluorodeschloroketamine
- Bromoketamine
- Methoxmetamine
- Trifluoromethyldeschloroketamine
- Rhynchophylline
References
- ↑ "Synthesis and in vitro evaluation of (18)F-labelled S-fluoroalkyl diarylguanidines: Novel high-affinity NMDA receptor antagonists for imaging with PET". Bioorganic & Medicinal Chemistry Letters 20 (5): 1749–51. March 2010. doi:10.1016/j.bmcl.2010.01.052. PMID 20138515.
- ↑ Stevens CL, "Aminoketones and methods for their production", US patent 3254124, published 31 May 1966
- ↑ "Characterization of the designer drug deschloroketamine (2-methylamino-2-phenylcyclohexanone) by gas chromatography/mass spectrometry, liquid chromatography/high-resolution mass spectrometry, multistage mass spectrometry, and nuclear magnetic resonance". Rapid Communications in Mass Spectrometry 30 (1): 151–60. January 2016. doi:10.1002/rcm.7425. PMID 26661982. Bibcode: 2016RCMS...30..151F.
- ↑ "Alerta: descloroketamina vendida como ketamina en Barcelona" (in Spanish). Energy Control. https://energycontrol.org/analisis-de-sustancias/resultados/alertas/560-alerta-descloroketamina-vendida-como-ketamina-en-barcelona.html.
- ↑ Villalba, Juanjo (27 March 2015). "Los efectos desconocidos de la sequía de ketamina" (in Spanish). Vice. https://www.vice.com/es/read/los-efectos-desconocidos-de-la-sequia-de-ketamina-719.
- ↑ Knibbs, Jeremy (22 October 2015). "Party-drug testing shows its worth". The Medical Republic. http://www.medicalrepublic.com.au/953-2/.
- ↑ "Synthesis and identification of deschloroketamine metabolites in rats' urine and a quantification method for deschloroketamine and metabolites in rats' serum and brain tissue using liquid chromatography tandem mass spectrometry". Drug Testing and Analysis 12 (3): 343–360. October 2019. doi:10.1002/dta.2726. PMID 31670910.
- ↑ Preiss D, Tatar A, "Use of 2-methylamino-2-phenylcyclohexanone for the treatment of bacterial, fungal, viral or protozoal infections and for immunomodulation", DE patent 4409671, published 23 May 1995
- ↑ "Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem" (in Latvian). Ministry of Health of the Republic of Latvia. http://www.vm.gov.lv/images/userfiles/metodiskas_vadlinijas_080914.doc.
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