Chemistry:CE-123
From HandWiki
Short description: Designer drug, analog of modafinil
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| Formula | C17H15NOS2 |
| Molar mass | 313.43 g·mol−1 |
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CE-123 is an analog of modafinil, the most researched of a series of structurally related heterocyclic derivatives.[1][2][3] In animal studies, CE-123 was found to improve performance on tests of learning and memory in a manner consistent with a nootropic effect profile.[4][5][6][7]
See also
References
- ↑ "A heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and dopamine D1-D3 containing receptor complexes". Neuropharmacology 102: 186–96. March 2016. doi:10.1016/j.neuropharm.2015.07.039. PMID 26407764.
- ↑ "A novel heterocyclic compound targeting the dopamine transporter improves performance in the radial arm maze and modulates dopamine receptors D1-D3". Behavioural Brain Research 312: 127–37. October 2016. doi:10.1016/j.bbr.2016.06.011. PMID 27288589.
- ↑ "A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat". Behavioural Brain Research 332: 308–315. August 2017. doi:10.1016/j.bbr.2017.06.023. PMID 28629964.
- ↑ "A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats". Frontiers in Behavioral Neuroscience 11: 222. 2017. doi:10.3389/fnbeh.2017.00222. PMID 29230168.
- ↑ "A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval". Behavioural Brain Research 343: 83–94. May 2018. doi:10.1016/j.bbr.2018.01.032. PMID 29410048.
- ↑ "Differential Effects of Novel Dopamine Reuptake Inhibitors on Interference With Long-Term Social Memory in Mice". Frontiers in Behavioral Neuroscience 13: 63. 2019. doi:10.3389/fnbeh.2019.00063. PMID 31031603.
- ↑ "(S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding". Frontiers in Pharmacology 10: 682. 2019. doi:10.3389/fphar.2019.00682. PMID 31316379.
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