Chemistry:5-MeO-DiBF

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Short description: Chemical compound
5-MeO-DiBF
5-MeO-DiBF.svg
5-MeO-DiBF 3D BS.png
Clinical data
Routes of
administration
?
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
  • US: ?
Identifiers
CAS Number
  • none
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H25NO2
Molar mass275.392 g·mol−1
3D model (JSmol)

5-MeO-DiBF is a psychedelic[1] that has been sold online as a designer drug and was first definitively identified in December 2015 by a forensic laboratory in Slovenia.[2] It is thought to act as an agonist for the 5-HT1A and 5-HT2 family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DiPT, but with the indole nitrogen replaced by oxygen, making 5-MeO-DiBF a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DiPT and with relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.[3][4]

Legal status

5-MeO-DiBF is not controlled under the 1971 Convention on Psychotropic Substances, so thus it has a legal grey area in many countries, but it's possible it could be illegal under so-called analogue acts if sold for human consumption.

See also

References

  1. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog". Microgram Journal 9 (1): 39–45. http://www.dea.gov/pr/microgram-journals/2012/mj9-1_39-45.pdf. 
  2. "Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA". European Monitoring Center for Drugs and Drug Addiction. http://www.emcdda.europa.eu/system/files/publications/2880/TDAS16001ENN.pdf. 
  3. "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry 35 (11): 2061–4. May 1992. doi:10.1021/jm00089a017. PMID 1534585. 
  4. "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology 29 (3): 193–8. March 1990. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.