Chemistry:7,N,N-TMT

Short description: Chemical compound

7,N,N-TMT

Identifiers
IUPAC name 2-(7-methyl-1H-indol-3-yl)-N,N-dimethylethanamine
CAS Number	65882-39-5 Y
PubChem CID	47747
ChemSpider	43445 Y
UNII	F9R59MT42E
ChEMBL	ChEMBL20167 Y
Chemical and physical data
Formula	C13H18N2
Molar mass	202.301 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C(NC=C2CCN(C)C)C2=CC=C1
InChI InChI=1S/C13H18N2/c1-10-5-4-6-12-11(7-8-15(2)3)9-14-13(10)12/h4-6,9,14H,7-8H2,1-3H3 Y Key:PQSFTUCFMWBITK-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

7,N,N-trimethyltryptamine (7-methyl-DMT, 7-TMT), is a tryptamine derivative which acts as an agonist of 5-HT₂ receptors. In animal tests, both 7-TMT and its 5-methoxy derivative 5-MeO-7-TMT produced behavioural responses similar to those of psychedelic drugs such as DMT, but the larger 7-ethyl and 7-bromo derivatives of DMT did not produce psychedelic responses despite having higher 5-HT₂ receptor affinity in vitro (cf. DOBU, DOAM). 7-TMT also weakly inhibits reuptake of serotonin but with little effect on dopamine or noradrenaline reuptake.

See also

• 2,N,N-TMT
• 5,N,N-TMT
• 7-Methyl-αET
• 7-Chloro-AMT