Biology:ZNF43
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Zinc finger protein 43 is a protein that in humans is encoded by the ZNF43 gene.[1][2]
Function
This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions.[2]
See also
References
- ↑ "A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines". Nucleic Acids Research 19 (11): 2921–8. Jun 1991. doi:10.1093/nar/19.11.2921. PMID 1711675.
- ↑ 2.0 2.1 "Entrez Gene: ZNF43 zinc finger protein 43". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7594.
Further reading
- "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". American Journal of Human Genetics 48 (4): 726–40. Apr 1991. PMID 2014798.
- "The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins". Proceedings of the National Academy of Sciences of the United States of America 88 (9): 3608–12. May 1991. doi:10.1073/pnas.88.9.3608. PMID 2023909. Bibcode: 1991PNAS...88.3608B.
- "Multiple genes encoding zinc finger domains are expressed in human T cells". The New Biologist 2 (4): 363–74. Apr 1990. PMID 2288909.
- "Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells". The EMBO Journal 12 (4): 1363–74. Apr 1993. doi:10.1002/j.1460-2075.1993.tb05781.x. PMID 8467795.
- "DNA cloning using in vitro site-specific recombination". Genome Research 10 (11): 1788–95. Nov 2000. doi:10.1101/gr.143000. PMID 11076863.
- "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports 1 (3): 287–92. Sep 2000. doi:10.1093/embo-reports/kvd058. PMID 11256614.
- "From ORFeome to biology: a functional genomics pipeline". Genome Research 14 (10B): 2136–44. Oct 2004. doi:10.1101/gr.2576704. PMID 15489336.
- "The LIFEdb database in 2006". Nucleic Acids Research 34 (Database issue): D415–8. Jan 2006. doi:10.1093/nar/gkj139. PMID 16381901.
- "Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells". Cancer Research 66 (24): 11932–7. Dec 2006. doi:10.1158/0008-5472.CAN-06-3220. PMID 17178891.
External links
- ZNF43+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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