Biology:HOXC12
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Homeobox C12 is a protein that in humans is encoded by the HOXC12 gene.[1]
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.[1]
References
Further reading
- "Complete mutation analysis panel of the 39 human HOX genes". Teratology 65 (2): 50–62. February 2002. doi:10.1002/tera.10009. PMID 11857506.
- "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. November 1992. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.
- "Nomenclature for human homeobox genes". Genomics 7 (3): 460. July 1990. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
- "The human HOX gene family". Nucleic Acids Research 17 (24): 10385–402. December 1989. doi:10.1093/nar/17.24.10385. PMID 2574852.
- "Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines". FEBS Letters 415 (3): 263–7. October 1997. doi:10.1016/S0014-5793(97)01118-6. PMID 9357979.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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