Biology:Testicular receptor

From HandWiki
Short description: Members of the nuclear receptor family of intracellular transcription factors
nuclear receptor subfamily 2, group C, member 1
Identifiers
SymbolNR2C1
Alt. symbolsTR2
NCBI gene7181
HGNC7971
OMIM601529
RefSeqNM_003297
UniProtP13056
Other data
LocusChr. 12 q22
nuclear receptor subfamily 2, group C, member 2
Identifiers
SymbolNR2C2
Alt. symbolsTR4
NCBI gene7182
HGNC7972
OMIM601426
RefSeqNM_003298
UniProtP49116
Other data
LocusChr. 3 p25

The testicular receptor proteins are members of the nuclear receptor family of intracellular transcription factors.[1] There are two forms of the receptor, TR2 and TR4, each encode by a separate gene (NR2C1 and NR2C2 respectively).[2][3][4]

References

  1. "Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily". J. Steroid Biochem. Mol. Biol. 81 (4–5): 291–308. 2002. doi:10.1016/S0960-0760(02)00118-8. PMID 12361719. 
  2. "Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains". Biochem. Biophys. Res. Commun. 165 (2): 735–41. 1989. doi:10.1016/S0006-291X(89)80028-2. PMID 2597158. 
  3. "New variants of the human and rat nuclear hormone receptor, TR4: expression and chromosomal localization of the human gene". Genomics 35 (2): 361–6. 1996. doi:10.1006/geno.1996.0368. PMID 8661150. 
  4. "Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily". Proc. Natl. Acad. Sci. U.S.A. 91 (13): 6040–4. 1994. doi:10.1073/pnas.91.13.6040. PMID 8016112. Bibcode1994PNAS...91.6040C. 

External links