Biology:ZNF202
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Zinc finger protein 202 is a transcription factor first associated with breast cancer. It is a protein that, in humans, is encoded by the ZNF202 gene.[1][2]
Clinical significance
Variants of this protein have been discovered to be strongly associated with coronary heart disease and atherosclerosis.[3]
References
- ↑ "Molecular cloning and characterization of ZNF202: a new gene at 11q23.3 encoding testis-specific zinc finger proteins". Genomics 52 (3): 358–362. September 1998. doi:10.1006/geno.1998.5419. PMID 9790754.
- ↑ "Entrez Gene: ZNF202 zinc finger protein 202". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=7753.
- ↑ "Zinc Finger Protein 202: a new candidate gene for ischemic heart disease: The Copenhagen City Heart Study". Atherosclerosis 188 (1): 43–50. September 2006. doi:10.1016/j.atherosclerosis.2005.10.014. PMID 16289551.
Further reading
- Zinc finger proteins: from atomic contact to cellular function. Molecular biology intelligence unit. Springer Japan Co., Ltd.. 2005. p. 161. ISBN 0-306-48229-0.
- "Antigens recognized by autologous antibody in patients with renal-cell carcinoma". International Journal of Cancer 83 (4): 456–464. November 1999. doi:10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5. PMID 10508479.
- "The SCAN domain mediates selective oligomerization". The Journal of Biological Chemistry 275 (22): 17173–17179. June 2000. doi:10.1074/jbc.M000119200. PMID 10747874.
- "A broad role for the zinc finger protein ZNF202 in human lipid metabolism". The Journal of Biological Chemistry 275 (21): 15685–15690. May 2000. doi:10.1074/jbc.M910152199. PMID 10748193.
- "The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux". The Journal of Biological Chemistry 276 (15): 12427–12433. April 2001. doi:10.1074/jbc.M100218200. PMID 11279031.
- "SDP1 is a peroxisome-proliferator-activated receptor gamma 2 co-activator that binds through its SCAN domain". The Biochemical Journal 370 (Pt 2): 719–727. March 2003. doi:10.1042/BJ20021378. PMID 12444922.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–1178. October 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "Zinc Finger Protein 202, genetic variation, and HDL cholesterol in the general population". Journal of Lipid Research 47 (5): 944–952. May 2006. doi:10.1194/jlr.M500521-JLR200. PMID 16467280.
External links
- ZNF202+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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