Biology:Nuclear factor I
From HandWiki
Short description: Family of transcription factors
Nuclear factor I (NF-I) is a family of closely related transcription factors. They constitutively bind as dimers to specific sequences of DNA with high affinity.[1] Family members contain an unusual DNA binding domain that binds to the recognition sequence 5'-TTGGCXXXXXGCCAA-3'.[2]
Subtypes include:
References
- ↑ "Increased nuclear factor 1 binding to its nucleosomal site mediated by sequence-dependent DNA structure". Nucleic Acids Res. 27 (2): 517–25. January 1999. doi:10.1093/nar/27.2.517. PMID 9862974.
- ↑ Walter F. Boron (2003). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. pp. 125–126. ISBN 1-4160-2328-3.
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