Biology:FOXF1
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Forkhead box protein F1 (FOXF1) is a protein that in humans is encoded by the FOXF1 gene.[1][2][3]
Function
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOX1 protein is important in the development of the pulmonary mesenchyme and the development of the gastrointestinal tract.[4]
References
- ↑ "Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12)". Genomics 30 (3): 464–9. Dec 1995. doi:10.1006/geno.1995.1266. PMID 8825632.
- ↑ "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". The EMBO Journal 13 (20): 5002–12. Oct 1994. doi:10.1002/j.1460-2075.1994.tb06827.x. PMID 7957066.
- ↑ "Entrez Gene: FOXF1 forkhead box F1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2294.
- ↑ "FOXF1 gene: MedlinePlus Genetics" (in en). https://medlineplus.gov/genetics/gene/foxf1/.
Further reading
- "Human brain factor 1, a new member of the fork head gene family". Genomics 21 (3): 551–7. Jun 1994. doi:10.1006/geno.1994.1313. PMID 7959731.
- "Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2". The Journal of Biological Chemistry 271 (8): 4482–90. Feb 1996. doi:10.1074/jbc.271.8.4482. PMID 8626802.
- "The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB". The Journal of Biological Chemistry 273 (36): 23335–43. Sep 1998. doi:10.1074/jbc.273.36.23335. PMID 9722567.
- "FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfaces". Developmental Biology 202 (2): 183–95. Oct 1998. doi:10.1006/dbio.1998.9010. PMID 9769171.
- "Differential epithelial expression of SHH and FOXF1 in usual and nonspecific interstitial pneumonia". Experimental and Molecular Pathology 80 (2): 119–23. Apr 2006. doi:10.1016/j.yexmp.2005.12.003. PMID 16448649.
- "Transcription factor FOXF1 regulates growth hormone variant gene expression". American Journal of Physiology. Endocrinology and Metabolism 291 (5): E947-51. Nov 2006. doi:10.1152/ajpendo.00128.2006. PMID 16772323.
External links
- FOXF1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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