Biology:ZBTB17

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene.

Interactions

ZBTB17 has been shown to interact with TOPBP1, Host cell factor C1 and Myc.

Further reading

• "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics 13 (4): 999–1007. Aug 1992. doi:10.1016/0888-7543(92)90013-I. PMID 1505991. 
• "Characterization and mapping of human genes encoding zinc finger proteins". Proceedings of the National Academy of Sciences of the United States of America 88 (21): 9563–7. Nov 1991. doi:10.1073/pnas.88.21.9563. PMID 1946370. Bibcode: 1991PNAS...88.9563B. 
• "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders". Genomics 27 (2): 259–64. May 1995. doi:10.1006/geno.1995.1040. PMID 7557990. 
• "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. Jan 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
• "Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA". Mechanisms of Development 65 (1–2): 3–17. Jul 1997. doi:10.1016/S0925-4773(97)00032-4. PMID 9256341. 
• "Association of Myc with the Zinc-finger Protein Miz-1 Defines a Novel Pathway for Gene Regulation by Myc". C-Myc in B-Cell Neoplasia. Current Topics in Microbiology and Immunology. 224. 1997. pp. 137–46. doi:10.1007/978-3-642-60801-8_14. ISBN 978-3-642-64560-0. 
• "An alternative pathway for gene regulation by Myc". The EMBO Journal 16 (18): 5672–86. Sep 1997. doi:10.1093/emboj/16.18.5672. PMID 9312026. 
• "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. Oct 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
• "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase". Archives of Biochemistry and Biophysics 382 (2): 262–74. Oct 2000. doi:10.1006/abbi.2000.2019. PMID 11068878. 
• "Repression of p15INK4b expression by Myc through association with Miz-1". Nature Cell Biology 3 (4): 392–9. Apr 2001. doi:10.1038/35070076. PMID 11283613. 
• "Transcription factor MIZ-1 is regulated via microtubule association". Molecular Cell 8 (2): 339–49. Aug 2001. doi:10.1016/S1097-2765(01)00313-6. PMID 11545736. 
• "The SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 is a transcriptional cofactor for TFII-I". The Journal of Biological Chemistry 277 (45): 43185–93. Nov 2002. doi:10.1074/jbc.M207635200. PMID 12193603. 
• "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of Biological Chemistry 277 (48): 46799–808. Nov 2002. doi:10.1074/jbc.M206226200. PMID 12244100. 
• "P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration". The Journal of Cell Biology 158 (7): 1287–97. Sep 2002. doi:10.1083/jcb.200207008. PMID 12356872. 
• "Negative regulation of the mammalian UV response by Myc through association with Miz-1". Molecular Cell 10 (3): 509–21. Sep 2002. doi:10.1016/S1097-2765(02)00633-0. PMID 12408820. 
• "Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter". Oncogene 22 (3): 351–60. Jan 2003. doi:10.1038/sj.onc.1206145. PMID 12545156. 
• "Characterization of the murine Nramp1 promoter: requirements for transactivation by Miz-1". The Journal of Biological Chemistry 278 (38): 36017–26. Sep 2003. doi:10.1074/jbc.M304301200. PMID 12840021. 
• "A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells". The Journal of Biological Chemistry 279 (15): 15505–14. Apr 2004. doi:10.1074/jbc.M310437200. PMID 14739298. 
• "A protein interaction framework for human mRNA degradation". Genome Research 14 (7): 1315–23. Jul 2004. doi:10.1101/gr.2122004. PMID 15231747. 

External links

• ZBTB17+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• Overview of all the structural information available in the PDB for UniProt: Q13105 (Zinc finger and BTB domain-containing protein 17) at the PDBe-KB.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.