Biology:Testicular receptor 2
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Short description: Human protein-coding gene
 Generic protein structure example |
The testicular receptor 2 (TR2) also known as NR2C1 (nuclear receptor subfamily 2, group C, member 1) is protein that in humans is encoded by the NR2C1 gene.[1][2] TR2 is a member of the nuclear receptor family of transcription factors.
Interactions
Testicular receptor 2 has been shown to interact with:
See also
References
- ↑ "Entrez Gene: NR2C1 nuclear receptor subfamily 2, group C, member 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7181.
- ↑ "Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains". Biochemical and Biophysical Research Communications 165 (2): 735–41. Dec 1989. doi:10.1016/S0006-291X(89)80028-2. PMID 2597158.
- ↑ "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3". The Prostate 57 (2): 129–33. Oct 2003. doi:10.1002/pros.10282. PMID 12949936.
- ↑ "Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor". The Journal of Biological Chemistry 277 (37): 33571–9. Sep 2002. doi:10.1074/jbc.M203531200. PMID 12093804.
- ↑ "Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2". Biochemical and Biophysical Research Communications 310 (2): 384–90. Oct 2003. doi:10.1016/j.bbrc.2003.08.145. PMID 14521922.
- ↑ 6.0 6.1 "Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase". Molecular and Cellular Endocrinology 206 (1–2): 1–12. Aug 2003. doi:10.1016/S0303-7207(03)00254-5. PMID 12943985.
- ↑ 7.0 7.1 "The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases". Molecular Endocrinology 15 (8): 1318–28. Aug 2001. doi:10.1210/mend.15.8.0682. PMID 11463856.
Further reading
- "Identification of a new member of the steroid receptor super-family by cloning and sequence analysis". Biochemical and Biophysical Research Communications 155 (2): 971–7. Sep 1988. doi:10.1016/S0006-291X(88)80591-6. PMID 3421977.
- "The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily". Endocrine 8 (2): 123–34. Apr 1998. doi:10.1385/ENDO:8:2:123. PMID 9704569.
- "A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4". The Journal of Biological Chemistry 273 (39): 25209–15. Sep 1998. doi:10.1074/jbc.273.39.25209. PMID 9737983.
- "Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2". Molecular and Cellular Biology 18 (11): 6745–55. Nov 1998. doi:10.1128/mcb.18.11.6745. PMID 9774688.
- "A constitutive nuclear localization signal from the second zinc-finger of orphan nuclear receptor TR2". The Journal of Endocrinology 159 (1): 53–60. Oct 1998. doi:10.1677/joe.0.1590053. PMID 9795341.
- "The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases". Molecular Endocrinology 15 (8): 1318–28. Aug 2001. doi:10.1210/mend.15.8.0682. PMID 11463856.
- "An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer". The EMBO Journal 21 (13): 3434–42. Jul 2002. doi:10.1093/emboj/cdf340. PMID 12093744.
- "Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor". The Journal of Biological Chemistry 277 (37): 33571–9. Sep 2002. doi:10.1074/jbc.M203531200. PMID 12093804.
- "Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes". Journal of Dermatological Science 31 (1): 65–71. Feb 2003. doi:10.1016/S0923-1811(02)00152-4. PMID 12615366.
- "Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase". Molecular and Cellular Endocrinology 206 (1–2): 1–12. Aug 2003. doi:10.1016/S0303-7207(03)00254-5. PMID 12943985.
- "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3". The Prostate 57 (2): 129–33. Oct 2003. doi:10.1002/pros.10282. PMID 12949936.
- "Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2". Biochemical and Biophysical Research Communications 310 (2): 384–90. Oct 2003. doi:10.1016/j.bbrc.2003.08.145. PMID 14521922.
- "Transcriptional regulation of the human TR2 orphan receptor gene by nuclear factor 1-A". Biochemical and Biophysical Research Communications 350 (2): 430–6. Nov 2006. doi:10.1016/j.bbrc.2006.09.061. PMID 17010934.
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