Biology:TOX2
From HandWiki
Short description: Mammalian protein found in Homo sapiens
| TOX high mobility group box family member 2 | |
|---|---|
| Identifiers | |
| Symbol | TOX2 |
| Alt. symbols | C20orf100, GCX-1 |
| NCBI gene | 84969 |
| HGNC | 16095 |
| OMIM | 611163 |
| RefSeq | NM_001098796 |
| UniProt | Q96NM4 |
| Other data | |
| Locus | Chr. 20 q13.12 |
TOX high mobility group box family member 2, also known as TOX2, is a human gene.[1][2]
The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.[3]
References
- ↑ "Entrez Gene: TOX high mobility group box family member 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84969.
- ↑ "Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells". Endocrinology 145 (5): 2307–18. May 2004. doi:10.1210/en.2003-1343. PMID 14764631.
- ↑ "TOX defines a conserved subfamily of HMG-box proteins". BMC Genomics 4 (1): 13. April 2003. doi:10.1186/1471-2164-4-13. PMID 12697058.
 |  |
