Biology:POU4F3

From HandWiki
Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene.[1][2] It's a member of BRN-3 group, also known as POU family class 4.

Nomenclature

DFNA15 refers to a type of nonsyndromic deafness, with autosomal dominant inheritance.

References

  1. "Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans". Science 279 (5358): 1950–4. Apr 1998. doi:10.1126/science.279.5358.1950. PMID 9506947. Bibcode1998Sci...279.1950V. 
  2. "Entrez Gene: POU4F3 POU domain, class 4, transcription factor 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5459. 

Further reading

In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.