Biology:GTF2E1

Short description: Human protein-coding gene

Generic protein structure example

General transcription factor IIE subunit 1 (GTF2E1), also known as transcription initiation factor IIE subunit alpha (TFIIE-alpha), is a protein that in humans is encoded by the GTF2E1 gene.

See also

• Transcription factor II E

Further reading

• "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme". Molecular Cell 27 (2): 262–74. July 2007. doi:10.1016/j.molcel.2007.06.027. PMID 17643375. 
• "Structural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II". The Journal of Biological Chemistry 276 (42): 38652–7. October 2001. doi:10.1074/jbc.M106422200. PMID 11509574. 
• "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study". Gynecologic Oncology 112 (1): 210–4. January 2009. doi:10.1016/j.ygyno.2008.09.012. PMID 18950845. 
• "Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from transcription initiation to elongation". Molecular and Cellular Biology 21 (1): 1–15. January 2001. doi:10.1128/MCB.21.1.1-15.2001. PMID 11113176. 
• "The carboxy terminus of the small subunit of TFIIE regulates the transition from transcription initiation to elongation by RNA polymerase II". Molecular and Cellular Biology 23 (8): 2914–26. April 2003. doi:10.1128/mcb.23.8.2914-2926.2003. PMID 12665589. 
• "Structure and oligomeric state of human transcription factor TFIIE". EMBO Reports 7 (5): 500–5. May 2006. doi:10.1038/sj.embor.7400663. PMID 16547462. 
• "The general transcription factors of RNA polymerase II". Genes & Development 10 (21): 2657–83. November 1996. doi:10.1101/gad.10.21.2657. PMID 8946909. 
• "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research 16 (1): 55–65. January 2006. doi:10.1101/gr.4039406. PMID 16344560. 
• "FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO". The Journal of Biological Chemistry 273 (42): 27593–601. October 1998. doi:10.1074/jbc.273.42.27593. PMID 9765293. 
• "Mechanism of ATP-dependent promoter melting by transcription factor IIH". Science 288 (5470): 1418–22. May 2000. doi:10.1126/science.288.5470.1418. PMID 10827951. Bibcode: 2000Sci...288.1418K. 
• "Involvement of negative cofactor NC2 in active repression by zinc finger-homeodomain transcription factor AREB6". Molecular and Cellular Biology 18 (1): 10–8. January 1998. doi:10.1128/mcb.18.1.10. PMID 9418848. 
• "Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split". Molecular and Cellular Biology 21 (14): 4614–25. July 2001. doi:10.1128/MCB.21.14.4614-4625.2001. PMID 11416139. 
• "p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH". Proceedings of the National Academy of Sciences of the United States of America 105 (1): 106–11. January 2008. doi:10.1073/pnas.0707892105. PMID 18160537. Bibcode: 2008PNAS..105..106D. 
• "MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity". The Journal of Biological Chemistry 284 (8): 5165–74. February 2009. doi:10.1074/jbc.M807098200. PMID 19106100. 
• "Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit". The Journal of Biological Chemistry 273 (31): 19866–76. July 1998. doi:10.1074/jbc.273.31.19866. PMID 9677423. 
• "A novel zinc finger structure in the large subunit of human general transcription factor TFIIE". The Journal of Biological Chemistry 279 (49): 51395–403. December 2004. doi:10.1074/jbc.M404722200. PMID 15385556. 
• "Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH". The EMBO Journal 27 (7): 1161–71. April 2008. doi:10.1038/emboj.2008.47. PMID 18354501. 
• "The putative cofactor TIF1alpha is a protein kinase that is hyperphosphorylated upon interaction with liganded nuclear receptors". The Journal of Biological Chemistry 273 (26): 16199–204. June 1998. doi:10.1074/jbc.273.26.16199. PMID 9632676. 
• "An atlas of combinatorial transcriptional regulation in mouse and man". Cell 140 (5): 744–52. March 2010. doi:10.1016/j.cell.2010.01.044. PMID 20211142.