Biology:GTF3C2

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

General transcription factor 3C polypeptide 2 is a protein that in humans is encoded by the GTF3C2 gene.

Interactions

GTF3C2 has been shown to interact with GTF3C4 and GTF3C5.

Further reading

• "The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC". J. Acquir. Immune Defic. Syndr. 5 (11): 1142–7. 1992. PMID 1403646. 
• "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Res. 1 (1): 27–35. 1994. doi:10.1093/dnares/1.1.27. PMID 7584026. 
• "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Res. 1 (1): 47–56. 1994. doi:10.1093/dnares/1.1.47. PMID 7584028. 
• "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. 1996. doi:10.1006/abio.1996.0138. PMID 8619474. 
• "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. 1997. doi:10.1101/gr.7.4.353. PMID 9110174. 
• "RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2". J. Biol. Chem. 272 (23): 14755–61. 1997. doi:10.1074/jbc.272.23.14755. PMID 9169441. 
• "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes". Nucleic Acids Res. 25 (12): 2440–7. 1997. doi:10.1093/nar/25.12.2440. PMID 9171097. 
• "DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III". Mol. Cell 1 (5): 749–57. 1998. doi:10.1016/S1097-2765(00)80074-X. PMID 9660958. 
• "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III". Mol. Cell. Biol. 19 (7): 4944–52. 1999. doi:10.1128/mcb.19.7.4944. PMID 10373544. 
• "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity". Mol. Cell. Biol. 19 (11): 7697–704. 1999. doi:10.1128/mcb.19.11.7697. PMID 10523658. 
• "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. 2004. doi:10.1101/gr.2435604. PMID 15342556. 
• "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R. 
• "A test of the model that RNA polymerase III transcription is regulated by selective induction of the 110 kDa subunit of TFIIIC". Nucleic Acids Res. 34 (11): 3399–407. 2006. doi:10.1093/nar/gkl432. PMID 16822860. 
• "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. 2006. doi:10.1038/nbt1240. PMID 16964243. 
• "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• "Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC". J. Biol. Chem. 282 (23): 17179–89. 2007. doi:10.1074/jbc.M611542200. PMID 17409385. 

External links

• GTF3C2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• FactorBook TFIIIC-110

This article incorporates text from the United States National Library of Medicine, which is in the public domain.