Biology:ZNF239

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Zinc finger protein 239 is a protein that in humans is encoded by the ZNF239 gene.[1][2][3]

Function

MOK2 proteins are DNA- and RNA-binding proteins that are mainly associated with nuclear RNP components, including the nucleoli and extranucleolar structures.[3][4]

Interactions

ZNF239 has been shown to interact with LMNA.[5]

References

  1. "Localization of zinc finger Mok2 gene to mouse chromosome 6, a new region of homology with human chromosome 19". Mammalian Genome 7 (1): 77–8. Jan 1996. doi:10.1007/s003359900020. PMID 8903737. 
  2. "Human and mouse Krüppel-like (MOK2) orthologue genes encode two different zinc finger proteins". Journal of Molecular Evolution 41 (6): 784–94. Dec 1995. doi:10.1007/bf00173158. PMID 8587123. Bibcode1995JMolE..41..784E. 
  3. 3.0 3.1 "Entrez Gene: ZNF239 zinc finger protein 239". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8187. 
  4. "Human and mouse MOK2 proteins are associated with nuclear ribonucleoprotein components and bind specifically to RNA and DNA through their zinc finger domains". Molecular and Cellular Biology 17 (4): 2116–26. Apr 1997. doi:10.1128/mcb.17.4.2116. PMID 9121460. 
  5. "In vivo and in vitro interaction between human transcription factor MOK2 and nuclear lamin A/C". Nucleic Acids Research 30 (21): 4634–42. Nov 2002. doi:10.1093/nar/gkf587. PMID 12409453. 

Further reading

\* "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research 16 (1): 55–65. Jan 2006. doi:10.1101/gr.4039406. PMID 16344560. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.