Biology:ZNF41
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Zinc finger protein 41 is a protein that in humans is encoded by the ZNF41 gene.[1][2]
This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23. Several alternatively spliced transcript variants have been described, however, the full-length nature of only some of them is known.[2]
References
- ↑ "Isolation and expression analysis of a human zinc finger gene (ZNF41) located on the short arm of the X chromosome". Genomics 9 (4): 728–36. Jul 1991. doi:10.1016/0888-7543(91)90367-N. PMID 2037297.
- ↑ 2.0 2.1 "Entrez Gene: ZNF41 zinc finger protein 41". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7592.
Further reading
- "Members of the zinc finger protein gene family sharing a conserved N-terminal module". Nucleic Acids Res. 19 (20): 5661–7. 1991. doi:10.1093/nar/19.20.5661. PMID 1945843.
- "Clustered organization of Krüppel zinc-finger genes at Xp11.23, flanking a translocation breakpoint at OATL1: a physical map with locus assignments for ZNF21, ZNF41, ZNF81, and ELK1". Genomics 21 (1): 180–7. 1994. doi:10.1006/geno.1994.1240. PMID 8088786.
- "Coding region intron/exon organization, alternative splicing, and X-chromosome inactivation of the KRAB/FPB-domain-containing human zinc finger gene ZNF41". Cytogenet. Cell Genet. 85 (3–4): 291–6. 1999. doi:10.1159/000015315. PMID 10449920.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation". Am. J. Hum. Genet. 73 (6): 1341–54. 2004. doi:10.1086/380309. PMID 14628291.
- "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. 2004. doi:10.1101/gr.2334104. PMID 15231748.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "The DNA sequence of the human X chromosome". Nature 434 (7031): 325–37. 2005. doi:10.1038/nature03440. PMID 15772651. Bibcode: 2005Natur.434..325R.
External links
- ZNF41+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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