Biology:MEIS1

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Short description: Protein-coding gene in humans


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Homeobox protein Meis1 is a protein that in humans is encoded by the MEIS1 gene.[1][2]

Function

Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.[2]

Interactions

MEIS1 has been shown to interact with PBX1[3][4][5] and HOXA9.[3][6]

References

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.