Biology:ZNF346

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Zinc finger protein 346 is a protein that in humans is encoded by the ZNF346 gene.[1][2]

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival.[2]

References

  1. "JAZ requires the double-stranded RNA-binding zinc finger motifs for nuclear localization". J Biol Chem 274 (39): 27399–406. Nov 1999. doi:10.1074/jbc.274.39.27399. PMID 10488071. 
  2. 2.0 2.1 "Entrez Gene: ZNF346 zinc finger protein 346". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23567. 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.