Biology:PBX3

Short description: Protein found in humans

Generic protein structure example

Pre-B-cell leukemia transcription factor 3 is a protein that in humans is encoded by the PBX3 gene.

Further reading

• "Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation". Mol. Cell. Biol. 14 (6): 3938–48. 1994. doi:10.1128/mcb.14.6.3938. PMID 7910944. 
• Shen WF; Rozenfeld S; Kwong A et al. (1999). "HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells". Mol. Cell. Biol. 19 (4): 3051–61. doi:10.1128/mcb.19.4.3051. PMID 10082572. 
• Fujino T; Yamazaki Y; Largaespada DA et al. (2001). "Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes". Exp. Hematol. 29 (7): 856–63. doi:10.1016/S0301-472X(01)00655-5. PMID 11438208. 
• "HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation". Oncogene 20 (39): 5440–8. 2001. doi:10.1038/sj.onc.1204710. PMID 11571641. 
• Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Humphray SJ; Oliver K; Hunt AR et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMID 15164053. Bibcode: 2004Natur.429..369H. 
• Rhee JW; Arata A; Selleri L et al. (2004). "Pbx3 Deficiency Results in Central Hypoventilation". Am. J. Pathol. 165 (4): 1343–50. doi:10.1016/S0002-9440(10)63392-5. PMID 15466398. 
• Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
• Rual JF; Venkatesan K; Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R. 

External links

• PBX3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• FactorBook Pbx3

This article incorporates text from the United States National Library of Medicine, which is in the public domain.