Biology:JUNB
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Transcription factor jun-B is a protein that in humans is encoded by the JUNB gene.[1][2] Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Interactions
JUNB has been shown to interact with
See also
- AP-1 (transcription factor)
References
- ↑ "jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun". Cell 59 (6): 987–997. Feb 1990. doi:10.1016/0092-8674(89)90755-1. PMID 2513129.
- ↑ "Entrez Gene: JUNB jun B proto-oncogene". https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&dopt=default&list_uids=3726&rn=1.
- ↑ "JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction". Genes Dev. 16 (12): 1509–17. Jun 2002. doi:10.1101/gad.995502. PMID 12080089.
- ↑ "Smads bind directly to the Jun family of AP-1 transcription factors". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 4844–9. Apr 1999. doi:10.1073/pnas.96.9.4844. PMID 10220381. Bibcode: 1999PNAS...96.4844L.
Further reading
- "Interactions among LRF-1, JunB, c-Jun, and c-Fos define a regulatory program in the G1 phase of liver regeneration". Mol. Cell. Biol. 12 (10): 4654–65. 1992. doi:10.1128/MCB.12.10.4654. PMID 1406655.
- "Expression of c-fos, c-jun, jun-B, metallothionein and metalloproteinase genes in human chondrocyte". FEBS Lett. 306 (2–3): 169–172. 1992. doi:10.1016/0014-5793(92)80992-P. PMID 1633872.
- "Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes". Biochem. J. 273(Pt 2) (2): 477–9. 1991. doi:10.1042/bj2730477. PMID 1899335.
- "Isolation of human cDNA clones of jun-related genes, jun-B and jun-D". Nucleic Acids Res. 18 (10): 3047–3048. 1990. doi:10.1093/nar/18.10.3047. PMID 2112242.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–174. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers". Genomics 15 (1): 133–145. 1993. doi:10.1006/geno.1993.1021. PMID 8432525. https://zenodo.org/record/1229582.
- "Complex genetic organization of junB: multiple blocks of flanking evolutionarily conserved sequence at the murine and human junB loci". Genomics 28 (2): 228–234. 1996. doi:10.1006/geno.1995.1135. PMID 8530030.
- "B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family". Oncogene 11 (11): 2255–65. 1996. PMID 8570175.
- "Expression of the jun family of genes in human ovarian cancer and normal ovarian surface epithelium". Oncogene 12 (6): 1247–57. 1996. PMID 8649827.
- "Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver". Proc. Natl. Acad. Sci. U.S.A. 93 (23): 12908–12913. 1996. doi:10.1073/pnas.93.23.12908. PMID 8917518. Bibcode: 1996PNAS...9312908M.
- "Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions". Mol. Cell. Biol. 17 (6): 3094–102. 1997. doi:10.1128/mcb.17.6.3094. PMID 9154808.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–156. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors". J. Biol. Chem. 272 (51): 32163–32168. 1998. doi:10.1074/jbc.272.51.32163. PMID 9405416.
- "Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes". Oncogene 17 (24): 3145–3156. 1999. doi:10.1038/sj.onc.1202237. PMID 9872330.
- "Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation". EMBO J. 18 (2): 420–432. 1999. doi:10.1093/emboj/18.2.420. PMID 9889198.
- "Smads bind directly to the Jun family of AP-1 transcription factors". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 4844–4849. 1999. doi:10.1073/pnas.96.9.4844. PMID 10220381. Bibcode: 1999PNAS...96.4844L.
- "Transactivation of naturally occurring HIV-1 long terminal repeats by the JNK signaling pathway. The most frequent naturally occurring length polymorphism sequence introduces a novel binding site for AP-1 factors". J. Biol. Chem. 275 (27): 20382–20390. 2000. doi:10.1074/jbc.M001149200. PMID 10764760.
- "B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos". Oncogene 19 (14): 1752–1763. 2000. doi:10.1038/sj.onc.1203491. PMID 10777209.
- "Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation". J. Biol. Chem. 275 (39): 30226–30231. 2000. doi:10.1074/jbc.M005310200. PMID 10903323. http://www.hal.inserm.fr/inserm-00150046.
- "JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin". Nature 9 (1): 3425. 2018. doi:10.1038/s41467-018-05726-z. PMID 30143626. Bibcode: 2018NatCo...9.3425S.
External links
- JUNB+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
 |  |
