Biology:MLLT1
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Protein ENL is a protein that in humans is encoded by the MLLT1 gene.[1]
Interactions
MLLT1 has been shown to interact with CBX8.[2]
References
- ↑ "Entrez Gene: MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4298.
- ↑ "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3". Oncogene 20 (4): 411–9. January 2001. doi:10.1038/sj.onc.1204108. PMID 11313972.
Further reading
- "Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias". Cell 71 (4): 691–700. November 1992. doi:10.1016/0092-8674(92)90602-9. PMID 1423624.
- "Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia". Proceedings of the National Academy of Sciences of the United States of America 91 (25): 12110–4. December 1994. doi:10.1073/pnas.91.25.12110. PMID 7991593. Bibcode: 1994PNAS...9112110T.
- "ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells". Blood 84 (6): 1747–52. September 1994. doi:10.1182/blood.V84.6.1747.1747. PMID 8080983.
- "Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia". Oncogene 8 (10): 2617–25. October 1993. PMID 8378076.
- "Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice". Proceedings of the National Academy of Sciences of the United States of America 97 (20): 10984–9. September 2000. doi:10.1073/pnas.190167297. PMID 10995463. Bibcode: 2000PNAS...9710984L.
- "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3". Oncogene 20 (4): 411–9. January 2001. doi:10.1038/sj.onc.1204108. PMID 11313972.
- "Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner". Molecular and Cellular Biology 23 (8): 2942–52. April 2003. doi:10.1128/MCB.23.8.2942-2952.2003. PMID 12665591.
- "Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited". BMC Cancer 6: 20. January 2006. doi:10.1186/1471-2407-6-20. PMID 16433901.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. November 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- "Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia". Leukemia 21 (3): 588–90. March 2007. doi:10.1038/sj.leu.2404542. PMID 17252016.
External links
- MLLT1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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