Biology:FOXN3
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Forkhead box protein N3 is a protein that in humans is encoded by the FOXN3 gene.[1][2]
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.[2]
See also
References
- ↑ "Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA". Mol Cell Biol 17 (6): 3037–46. Jun 1997. doi:10.1128/MCB.17.6.3037. PMID 9154802.
- ↑ 2.0 2.1 "Entrez Gene: CHES1 checkpoint suppressor 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1112.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Susceptibility to insulin-dependent diabetes mellitus maps to a locus (IDDM11) on human chromosome 14q24.3-q31.". Genomics 33 (1): 1–8. 1996. doi:10.1006/geno.1996.0153. PMID 8617492.
- "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807–28. 1997. doi:10.1101/gr.6.9.807. PMID 8889549.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.". Genome Res. 11 (8): 1392–403. 2001. doi:10.1101/gr.175501. PMID 11483580.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The DNA sequence and analysis of human chromosome 14.". Nature 421 (6923): 601–7. 2003. doi:10.1038/nature01348. PMID 12508121. Bibcode: 2003Natur.421..601H.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. 2004. doi:10.1101/gr.2122004. PMID 15231747.
- "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. 2004. doi:10.1101/gr.2435604. PMID 15342556.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor.". Gene 359: 119–26. 2005. doi:10.1016/j.gene.2005.06.014. PMID 16102918.
- "Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response.". Cancer Res. 66 (17): 8397–403. 2007. doi:10.1158/0008-5472.CAN-06-0061. PMID 16951149.
- "Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.". Gastroenterology 133 (5): 1475–86. 2007. doi:10.1053/j.gastro.2007.08.038. PMID 17983802.
External links
- CHES1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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