Biology:POU4F3
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene.[1][2] It's a member of BRN-3 group, also known as POU family class 4.
Nomenclature
DFNA15 refers to a type of nonsyndromic deafness, with autosomal dominant inheritance.
References
- ↑ "Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans". Science 279 (5358): 1950–4. Apr 1998. doi:10.1126/science.279.5358.1950. PMID 9506947. Bibcode: 1998Sci...279.1950V.
- ↑ "Entrez Gene: POU4F3 POU domain, class 4, transcription factor 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5459.
Further reading
In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice
- "Identification and functional analysis of common sequence variants in the DFNA15 gene, Brn-3c.". Gene 400 (1–2): 89–97. 2017. doi:10.1016/j.gene.2007.05.023. PMID 17611044. http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30390-X.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity". Biochem. Biophys. Res. Commun. 324 (1): 372–81. 2004. doi:10.1016/j.bbrc.2004.09.074. PMID 15465029.
- "The DFNA15 Deafness Mutation Affects POU4F3 Protein Stability, Localization, and Transcriptional Activity". Mol. Cell. Biol. 23 (22): 7957–64. 2003. doi:10.1128/MCB.23.22.7957-7964.2003. PMID 14585957.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma". Int. J. Cancer 101 (2): 103–10. 2002. doi:10.1002/ijc.10554. PMID 12209986.
- "Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development". Nature 381 (6583): 603–6. 1996. doi:10.1038/381603a0. PMID 8637595. Bibcode: 1996Natur.381..603E.
- "The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons". J. Neurosci. 15 (7 Pt 1): 4762–85. 1995. doi:10.1523/JNEUROSCI.15-07-04762.1995. PMID 7623109.
External links
- POU4F3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
 |  |
