Biology:NFE2
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene.[1][2]
It is involved in megakaryocyte production.[3]
Interactions
NFE2 has been shown to interact with CREB-binding protein.[4]
References
- ↑ "Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner". Mol Cell Biol 13 (9): 5604–12. Sep 1993. doi:10.1128/mcb.13.9.5604. PMID 8355703.
- ↑ "Entrez Gene: NFE2 nuclear factor (erythroid-derived 2), 45kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4778.
- ↑ "Regulation and function of the NFE2 transcription factor in hematopoietic and non-hematopoietic cells". Cellular and Molecular Life Sciences 72 (12): 2323–2335. 2015. doi:10.1007/s00018-015-1866-6. PMID 25721735.
- ↑ "Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation". J. Biol. Chem. 276 (14): 10715–21. Apr 2001. doi:10.1074/jbc.M007846200. PMID 11154691.
Further reading
- "In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.". Mol. Cell. Biol. 12 (5): 2135–42. 1992. doi:10.1128/MCB.12.5.2135. PMID 1569944.
- "Isolation of a differentially regulated splicing isoform of human NF-E2". Proc. Natl. Acad. Sci. U.S.A. 92 (8): 3511–5. 1995. doi:10.1073/pnas.92.8.3511. PMID 7724591. Bibcode: 1995PNAS...92.3511P.
- "Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development". Cell 81 (5): 695–704. 1995. doi:10.1016/0092-8674(95)90531-6. PMID 7774011.
- "Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins". Nature 367 (6463): 568–72. 1994. doi:10.1038/367568a0. PMID 8107826. Bibcode: 1994Natur.367..568I.
- "Isolation of cDNA encoding the human NF-E2 protein". Proc. Natl. Acad. Sci. U.S.A. 90 (23): 11366–70. 1994. doi:10.1073/pnas.90.23.11366. PMID 8248255.
- "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif". Oncogene 14 (16): 1901–10. 1997. doi:10.1038/sj.onc.1201024. PMID 9150357.
- "Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression". Blood 89 (11): 3925–35. 1997. doi:10.1182/blood.V89.11.3925. PMID 9166829.
- "Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II". J. Biol. Chem. 272 (39): 24105–8. 1997. doi:10.1074/jbc.272.39.24105. PMID 9305852.
- "Physical and functional interactions between the transactivation domain of the hematopoietic transcription factor NF-E2 and WW domains". Biochemistry 37 (39): 13686–95. 1998. doi:10.1021/bi981310l. PMID 9753456.
- "Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation". J. Biol. Chem. 276 (14): 10715–21. 2001. doi:10.1074/jbc.M007846200. PMID 11154691.
- "NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor". Genomics 79 (3): 423–31. 2002. doi:10.1006/geno.2002.6714. PMID 11863372.
- "Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins". J. Biol. Chem. 277 (44): 41563–70. 2003. doi:10.1074/jbc.M208184200. PMID 12196550.
- "Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation". Blood Cells Mol. Dis. 29 (2): 145–58. 2003. doi:10.1006/bcmd.2002.0550. PMID 12490281.
- "Interaction of NF-E2 in the human beta-globin locus control region before chromatin remodeling". J. Biol. Chem. 278 (10): 8163–71. 2003. doi:10.1074/jbc.M209612200. PMID 12509425.
- "Comprehensive identification of human bZIP interactions with coiled-coil arrays". Science 300 (5628): 2097–101. 2003. doi:10.1126/science.1084648. PMID 12805554. Bibcode: 2003Sci...300.2097N.
- "Interleukin-1beta up-regulates the expression of thrombopoietin and transcription factors c-Jun, c-Fos, GATA-1, and NF-E2 in megakaryocytic cells". J. Lab. Clin. Med. 143 (2): 75–88. 2004. doi:10.1016/j.lab.2003.09.006. PMID 14966463.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
External links
- NFE2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- FactorBook NF-E2
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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