Biology:HBP1

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

HMG-box transcription factor 1, also known as HBP1, is a human protein.

Interactions

HBP1 has been shown to interact with SIN3A and Retinoblastoma protein.

Further reading

• "HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family.". Genes Dev. 11 (3): 383–96. 1997. doi:10.1101/gad.11.3.383. PMID 9030690. 
• "The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A.". Oncogene 14 (22): 2721–8. 1997. doi:10.1038/sj.onc.1201243. PMID 9178770. 
• "Human HMG box transcription factor HBP1: a role in hCD2 LCR function". EMBO J. 18 (22): 6396–406. 2000. doi:10.1093/emboj/18.22.6396. PMID 10562551. 
• "Involvement of Retinoblastoma Protein and HBP1 in Histone H10 Gene Expression". Mol. Cell. Biol. 20 (18): 6627–37. 2000. doi:10.1128/MCB.20.18.6627-6637.2000. PMID 10958660. 
• "HMG Box Transcriptional Repressor HBP1 Maintains a Proliferation Barrier in Differentiated Liver Tissue". Mol. Cell. Biol. 21 (17): 5723–32. 2001. doi:10.1128/MCB.21.17.5723-5732.2001. PMID 11486012. 
• "Negative regulation of the Wnt–β-catenin pathway by the transcriptional repressor HBP1". EMBO J. 20 (16): 4500–11. 2001. doi:10.1093/emboj/20.16.4500. PMID 11500377. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. 2003. doi:10.1038/nature01782. PMID 12853948. Bibcode: 2003Natur.424..157H. 
• "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039. 
• "Assignment of the 1H, 13C, and 15N resonances of the AXH domain of the transcription factor HBP1". J. Biomol. NMR 28 (4): 411–2. 2004. doi:10.1023/B:JNMR.0000015367.92295.0f. PMID 14872137. 
• "HBP1 Repression of the p47phox Gene: Cell Cycle Regulation via the NADPH Oxidase". Mol. Cell. Biol. 24 (7): 3011–24. 2004. doi:10.1128/MCB.24.7.3011-3024.2004. PMID 15024088. 
• "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. 2004. doi:10.1101/gr.2334104. PMID 15231748. 
• "HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations". Nat. Struct. Mol. Biol. 11 (8): 738–46. 2004. doi:10.1038/nsmb798. PMID 15235594. 
• "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells". Leukemia 19 (11): 1958–68. 2005. doi:10.1038/sj.leu.2403918. PMID 16179914. 
• "Towards a proteome-scale map of the human protein–protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R. 
• "Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation". J. Immunol. 175 (8): 5203–12. 2005. doi:10.4049/jimmunol.175.8.5203. PMID 16210625. 
• "Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1". J. Biol. Chem. 281 (16): 10865–75. 2006. doi:10.1074/jbc.M513378200. PMID 16495219. 
• "A protein–protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell 125 (4): 801–14. 2006. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
• "The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence". Mol. Cell. Biol. 26 (22): 8252–66. 2007. doi:10.1128/MCB.00604-06. PMID 16966377. 

External links

• HBP1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)