Biology:DTX2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Protein deltex-2 also known as E3 ubiquitin-protein ligase DTX2 is an enzyme that in humans is encoded by the DTX2 gene.[1]
DTX2 functions as a ubiquitin E3 ligase in conjunction with the E2 enzyme UBCH5A.[2]
References
- ↑ "Entrez Gene: DTX2 deltex homolog 2 (Drosophila)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=113878.
- ↑ "The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity". J. Biol. Chem. 278 (24): 21930–7. 2003. doi:10.1074/jbc.M301157200. PMID 12670957.
Further reading
- Matsuno K; Diederich RJ; Go MJ et al. (1995). "Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats". Development 121 (8): 2633–44. doi:10.1242/dev.121.8.2633. PMID 7671825.
- Kishi N; Tang Z; Maeda Y et al. (2001). "Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis". Int. J. Dev. Neurosci. 19 (1): 21–35. doi:10.1016/S0736-5748(00)00071-X. PMID 11226752.
- Yamamoto N; Yamamoto S; Inagaki F et al. (2002). "Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor". J. Biol. Chem. 276 (48): 45031–40. doi:10.1074/jbc.M105245200. PMID 11564735.
- Benzinger A; Muster N; Koch HB et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell. Proteomics 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465.
- Hiller M; Huse K; Szafranski K et al. (2007). "Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing". Am. J. Hum. Genet. 78 (2): 291–302. doi:10.1086/500151. PMID 16400609.
- Lim J; Hao T; Shaw C et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- "cDNA cloning, characterization and expression analysis of DTX2, a human WWE and RING-finger gene, in human embryos". DNA Seq. 17 (3): 175–80. 2007. doi:10.1080/10425170600857616. PMID 17286044.
External links
- DTX2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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