Biology:IRF9
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G.[1][2][3]
Interactions
IRF9 has been shown to interact with STAT2[4][5] and STAT1.[4]
References
- ↑ "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins". Mol Cell Biol 12 (8): 3315–24. Aug 1992. doi:10.1128/MCB.12.8.3315. PMID 1630447.
- ↑ "Organization of the genes encoding the human proteasome activators PA28alpha and beta". Immunogenetics 49 (5): 438–45. Jun 1999. doi:10.1007/s002510050517. PMID 10199920.
- ↑ "Entrez Gene: ISGF3G interferon-stimulated transcription factor 3, gamma 48kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10379.
- ↑ 4.0 4.1 Horvath, C M; Stark G R; Kerr I M; Darnell J E (Dec 1996). "Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex". Mol. Cell. Biol. (UNITED STATES) 16 (12): 6957–64. doi:10.1128/mcb.16.12.6957. ISSN 0270-7306. PMID 8943351.
- ↑ Martinez-Moczygemba, M; Gutch M J; French D L; Reich N C (Aug 1997). "Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3". J. Biol. Chem. (UNITED STATES) 272 (32): 20070–6. doi:10.1074/jbc.272.32.20070. ISSN 0021-9258. PMID 9242679.
Further reading
- "Viral inhibition of interferon signal transduction". Intervirology 42 (5–6): 325–30. 2000. doi:10.1159/000053968. PMID 10702714.
- Reich NC (2002). "Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation". J. Interferon Cytokine Res. 22 (1): 103–9. doi:10.1089/107999002753452719. PMID 11846981.
- "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening". Genomics 23 (1): 42–50. 1995. doi:10.1006/geno.1994.1457. PMID 7829101.
- "In vitro activation of the transcription factor ISGF3 by interferon alpha involves a membrane-associated tyrosine phosphatase and tyrosine kinase". J. Biol. Chem. 268 (9): 6593–9. 1993. doi:10.1016/S0021-9258(18)53292-0. PMID 8454630.
- "Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex". Mol. Cell. Biol. 16 (12): 6957–64. 1997. doi:10.1128/mcb.16.12.6957. PMID 8943351.
- "Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3". J. Biol. Chem. 272 (32): 20070–6. 1997. doi:10.1074/jbc.272.32.20070. PMID 9242679.
- "Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method". Genomics 46 (2): 174–82. 1998. doi:10.1006/geno.1997.5044. PMID 9417904. https://zenodo.org/record/1229747.
- "Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors". Proc. Natl. Acad. Sci. U.S.A. 97 (13): 7278–83. 2000. doi:10.1073/pnas.97.13.7278. PMID 10860992. Bibcode: 2000PNAS...97.7278L.
- "A Novel Interferon Regulatory Factor (IRF), IRF-10, Has a Unique Role in Immune Defense and Is Induced by the v-Rel Oncoprotein". Mol. Cell. Biol. 22 (11): 3942–57. 2002. doi:10.1128/MCB.22.11.3942-3957.2002. PMID 11997525.
- "Resistance to interferons in melanoma cells does not correlate with the expression or activation of signal transducer and activator of transcription 1 (Stat1)". J. Interferon Cytokine Res. 22 (5): 603–13. 2002. doi:10.1089/10799900252982089. PMID 12060499.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Role of Metazoan Mediator Proteins in Interferon-Responsive Transcription". Mol. Cell. Biol. 23 (2): 620–8. 2003. doi:10.1128/MCB.23.2.620-628.2003. PMID 12509459.
- "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones". DNA Res. 10 (1): 49–57. 2003. doi:10.1093/dnares/10.1.49. PMID 12693554.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Identification of the protein Zibra, its genomic organization, regulation, and expression in breast cancer cells". Exp. Cell Res. 295 (2): 448–59. 2004. doi:10.1016/j.yexcr.2004.01.019. PMID 15093743.
- "Histone deacetylase activity is required to recruit RNA polymerase II to the promoters of selected interferon-stimulated early response genes". J. Biol. Chem. 279 (39): 40362–7. 2004. doi:10.1074/jbc.M406400200. PMID 15194680.
External links
- ISGF3G+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- IRF9 human gene location in the UCSC Genome Browser.
- IRF9 human gene details in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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