Biology:KDM5D
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Lysine-specific demethylase 5D is an enzyme that in humans is encoded by the KDM5D gene.[1][2][3] KDM5D belongs to the alpha-ketoglutarate-dependent hydroxylases superfamily.
This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient.[3]
References
- ↑ "The foundation of the "Inst" medical department and its association with the Belfast Fever Hospital". The Ulster Medical Journal 45 (2): 107–45. Feb 1977. PMID 795123.
- ↑ "Gene sequence and evolutionary conservation of human SMCY". Nature Genetics 14 (2): 128–9. October 1996. doi:10.1038/ng1096-128. PMID 8841177.
- ↑ 3.0 3.1 "Entrez Gene: JARID1D jumonji, AT rich interactive domain 1D". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8284.
Further reading
- "The male-specific histocompatibility antigen, H-Y: a history of transplantation, immune response genes, sex determination and expression cloning". Annual Review of Immunology 15: 39–61. 1997. doi:10.1146/annurev.immunol.15.1.39. PMID 9143681.
- "The serologically detected H-Y antigen revisited". Cytogenetics and Cell Genetics 80 (1–4): 232–5. 1998. doi:10.1159/000014986. PMID 9678364.
- "A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens". Human Molecular Genetics 3 (6): 873–8. June 1994. doi:10.1093/hmg/3.6.873. PMID 7524912.
- "Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein". Science 269 (5230): 1588–90. September 1995. doi:10.1126/science.7667640. PMID 7667640. Bibcode: 1995Sci...269.1588W.
- "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Research 3 (5): 321–9, 341–54. October 1996. doi:10.1093/dnares/3.5.321. PMID 9039502.
- "Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven". Mammalian Genome 8 (2): 134–8. February 1997. doi:10.1007/s003359900372. PMID 9060413.
- "HA-1 and the SMCY-derived peptide FIDSYICQV (H-Y) are immunodominant minor histocompatibility antigens after bone marrow transplantation". Transplantation 66 (7): 910–6. October 1998. doi:10.1097/00007890-199810150-00016. PMID 9798702.
- "Expression analysis of thirty one Y chromosome genes in human prostate cancer". Molecular Carcinogenesis 27 (4): 308–21. April 2000. doi:10.1002/(SICI)1098-2744(200004)27:4<308::AID-MC9>3.0.CO;2-R. PMID 10747295.
- "Population genetic implications from sequence variation in four Y chromosome genes". Proceedings of the National Academy of Sciences of the United States of America 97 (13): 7354–9. June 2000. doi:10.1073/pnas.97.13.7354. PMID 10861003. Bibcode: 2000PNAS...97.7354S.
- "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes". Nature 423 (6942): 825–37. June 2003. doi:10.1038/nature01722. PMID 12815422. Bibcode: 2003Natur.423..825S.
- "Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches". Molecular Biology and Evolution 21 (2): 384–96. February 2004. doi:10.1093/molbev/msh027. PMID 14660691.
- "Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission". Blood 105 (7): 2973–8. April 2005. doi:10.1182/blood-2004-09-3660. PMID 15613541.
- "Functional HY-specific CD8+ T cells are found in a high proportion of women following pregnancy with a male fetus". Biology of Reproduction 76 (1): 96–101. January 2007. doi:10.1095/biolreprod.106.055426. PMID 16988213.
- "The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases". Cell 128 (6): 1077–88. March 2007. doi:10.1016/j.cell.2007.02.017. PMID 17320160.
- "Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein". Cell 128 (5): 877–87. March 2007. doi:10.1016/j.cell.2007.02.004. PMID 17320162.
External links
- JARID1D+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Overview of all the structural information available in the PDB for UniProt: Q9BY66 (Lysine-specific demethylase 5D) at the PDBe-KB.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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