Chemistry:2C-AL

From HandWiki
Short description: Chemical compound
2C-AL
2C-AL structure.png
Identifiers
CAS Number
PubChem CID
Chemical and physical data
FormulaC13H19NO2
Molar mass221.300 g·mol−1
3D model (JSmol)

2C-AL is a drug from the substituted phenethylamine family which acts as an agonist of the 5-HT2A receptor, with an EC50 of 2.15nM at 5-HT2A vs 77.71nM at 5-HT2B, and produces a head-twitch response in animal studies. It was first discussed as a hypothetical compound in Daniel Trachsel's 2013 review of the field after his successful synthesis of the related compounds 2C-V and 2C-YN,[1] and finally synthesised by a team at Gilgamesh Pharmaceuticals in 2020 using a different synthetic route from that employed by Trachsel.[2]

See also

References

  1. Phenethylamine Von der Struktur zur Funktion. Nachtschatten Verlag AG. 2013. p. 768. ISBN 978-3-03788-700-4. 
  2. Kruegel AC, "Phenalkylamines and Methods of Treating Mood Disorders", WO patent 2022/006186